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        Isaac Guerendo Injury History & Analysis

        Isaac Guerendo's Injury Guide

        Medium Risk

        Chance of Injury in 2025

        58%

        % chance misses at least 2 quarters

        Chance of Injury per Game

        5%

        1- 17√1-% Inj/Season

        Projected Games Missed 2025

        2.57

        Durability

        5.00

        Ability to produce despire relatively minor injuries. 5 being most durable

        Injury analysis powered by Draft Sharks Injury Guide, formerly Sports Injury Predictor

        Isaac Guerendo's Injury Status

        No active injuries.

        Isaac Guerendo Injury History

        Date League Injury Games Missed Details
        Aug 2, 2025
        NFL Shoulder Unspecified Unspecified
        Grade 1
        - Guerendo suffered an apparent shoulder injury during special-teams drills.
        Jan 5, 2025
        NFL Knee MCL Pull
        Grade 1
        - Guerendo suffered knee and ankle injuries in the regular-season finale loss to the Cardinals.
        Dec 18, 2024
        NFL Thigh Hamstring Sprain/Pull
        Unspecified Grade 1
        1 Guerendo was ruled out for Week 16's game at Miami due to a hamstring injury.
        Dec 8, 2024
        NFL Pedal Foot Sprain
        Grade 1
        - Guerendo suffered a foot injury in the fourth quarter of Week 14's game vs. the Bears.
        Jul 24, 2024
        NFL Thigh Hamstring Sprain/Pull
        Unspecified Grade 1
        - Guerendo injured his hamstring during training camp practice but recovered in time for the preseason game against Las Vegas.
        Oct 2, 2021
        NFL Pedal Ankle Ligament
        Tear Grade 3
        8 Guerendo suffered a season-ending ankle injury against Michigan. He was out for the spring
        How do Injuries impact your draft strategy?

        For us, it's 1/17th of the equation. Hear us out.

        The Draft War Room is the only live-sync draft tool that monitors 17 crucial in-draft indicators, including injury likelihood… and adapts to show you which players to pick throughout your draft.

        Dominate Your League

        Isaac Guerendo Injury News

        Isaac Guerendo Returns To Practice Tuesday
        8:08pm UTC 8/19/25

        Isaac Guerendo Returns To Practice Tuesday

        49ers’ second-string RB Isaac Guerendo returned to practice on Tuesday, according to Nick Wagoner of ESPN. Guerendo had been sidelined for multiple weeks with a shoulder injury.

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        Isaac Guerendo

        Isaac Guerendo
        Player Profile

        RB SF

        Height

        6'0"

        Weight

        221 lbs.

        Experience

        1 yrs.

        Bye

        14

        Birthday

        Jun 28, 2000

        Age

        25.2

        College

        Louisville

        NFL Draft Pick

        2024 - Rd 4, Pk 129

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