ESPN's Adam Schefter reports that 49ers RB Isaac Guerendo is "unlikely to play" Sunday at Miami because of his hamstring injury.

49ers RB Isaac Guerendo (foot, hamstring) did not practice on Wednesday. He played through the foot issue last Thursday night, but the hamstring is new. We'll see if he's able to practice tomorrow. Patrick Taylor would be San Francisco's lead back vs. the Dolphins on Sunday if Guerendo can't go.

49ers RB Isaac Guerendo (foot) is active for tonight's game vs. the Rams. He was listed as questionable after only getting in a limited practice on Tuesday. But Guerendo downplayed the injury throughout the week and was reportedly expected to play tonight even before getting through warmups. There have been no reports so far about the rookie's expected workload in this one. He shapes up as a risk/reward fantasy play. Check the new-and-improved Who To Start Tool to see if Guerendo makes sense for your starting lineup. RBs Patrick Taylor and Ke'Shawn Vaughn are also active for San Francisco tonight; RB Israel Abanikanda is a healthy scratch.

49ers RB Isaac Guerendo plans to play tonight despite his sprained foot. There was doubt over him playing after being injured and sitting out part of the game last week. If Guerendo does not have a full workload due to the injury, RB Patrick Taylor will get a bigger share of touches.