Titans QB Cam Ward suffered a shoulder injury in the first quarter of Sunday's game vs. the Jaguars and is questionable to return. He's been replaced by QB Brandon Allen. We'll update Ward's status when we know more. He's had a promising finish to his rookie season and could be an intriguing QB2 target in 2026 fantasy drafts.

Update: Ward has been ruled out.

49ers QB Brock Purdy (shoulder) is active for tonight’s game vs. the Bills. He had a good week by all accounts, progressing to a full practice on Friday. There’s still elevated risk to using Purdy in fantasy lineups with the throwing shoulder issue, though. And the spot is tough against the Bills’ ninth-ranked QB defense in wintery Buffalo. Purdy is not a recommended QB1 play – but his return is good news for San Francisco’s skill-position players. QB Brandon Allen is inactive as the emergency third QB tonight, leaving QB Josh Dobbs as the backup.

49ers QB Brock Purdy (shoulder) remains uncertain for Sunday night's game vs. the Bills, according to NFL Network's Ian Rapoport. Purdy was "very limited" in Wednesday's practice, Rapoport adds. "Probably needs to improve just a little bit to be able to get on the field" against the Bills. QB Brandon Allen mustered just 199 passing yards and one TD on 6.9 yards per attempt last week and would be a big downgrade for San Francisco's offense if he starts again.

49ers QB Brock Purdy (shoulder) did some "light throwing" on Monday and felt good, HC Kyle Shanahan said. “We didn’t push him that hard,” Shanahan added. “But he did some light throwing, which was a good sign. We’ll rest him tomorrow and see how he feels as the week goes.” Two MRIs on Purdy's throwing shoulder last week -- one on Monday, one on Thursday -- revealed no structural damage. Purdy seemingly has a chance to return for Sunday night's game vs. the Bills, but we'll keep you updated on his progress throughout the week. Shanahan said QB Brandon Allen would get another start in Buffalo if Purdy is out.

49ers QB Brock Purdy (shoulder) is out for Sunday's game vs. the Packers. His injured right shoulder evidently didn't progress throughout the week as the team had hoped. GM John Lynch said Friday that an MRI on the shoulder didn't show anything concerning, so we're not expecting this to be a long-term absence. But Purdy's absence this weekend leaves QB Brandon Allen as San Francisco's expected starter. Allen has been with the 'Niners since May 2023 but has not attempted a regular-season pass for them. He completed just 57% of his passes at 6.1 yards per attempt in limited action for the Broncos and Bengals from 2019-2022. Allen is clearly a significant downgrade for all San Francisco pass catchers. Expect the team to lean heavily on RB Christian McCaffrey on Sunday.

49ers GM John Lynch said Friday morning that QB Brock Purdy had an MRI on his right shoulder. "Feel good about where it is from that standpoint," Lynch said. But he stopped short of saying that Purdy will play vs. the Packers this weekend. "Brock will show up here today, see where he goes from practice, go forth accordingly," Lynch said. He added that QB Brandon Allen would get the start if Purdy is out but that QB Josh Dobbs would also "be ready." We'll update Purdy's status again this afternoon.

49ers QB Brock Purdy (shoulder) was officially limited again in Thursday's practice. According to insider Grant Cohn, Purdy tried to warm up at the start of practice but was clearly uncomfortable and then headed inside with trainers. "He was still limited today," HC Kyle Shanahan said afterward. "He didn't do as much yesterday but did a little bit more today. He went out there and did a little bit then went back in about halfway through and rested up. Hopefully it will be feeling great on Sunday." We're certainly more worried about Purdy's Week 12 status now than we were at this point yesterday. We'll update the situation again on Friday. QB Brandon Allen would likely get the start vs. the Packers this weekend if Purdy is out.

49ers QB Brock Purdy is "day to day" with soreness in his right (throwing) shoulder, HC Kyle Shanahan said Monday. Shanahan said the soreness is from a hit Purdy took in the Week 11 loss to the Seahawks. This doesn't sound like a serious injury, but a throwing shoulder injury on a QB is always worth monitoring closely. QB Brandon Allen is listed with the second team on San Francisco's depth chart; Joshua Dobs with the third team.