Christian McCaffrey Fantasy Football News | Shark Bites

49ers QB Brock Purdy (toe, shoulder) is a "long shot" to play vs. the Saints this weekend, HC Kyle Shanahan said Wednesday. Shanahan added that Purdy could be looking at a multi-week absence. SI's Grant Cohn hears that the team is expecting Purdy to miss two games. His absence will leave QB Mac Jones under center.

The 49ers placed TE George Kittle on Injured Reserve. Kittle will miss a minimum of 4 games.

Niners RB Christian McCaffrey might have been questionable entering the weekend, but you wouldn't have known it by the way the team used him in the victory over Seattle. McCaffrey rushed 22 times and caught nine of 10 targets Sunday. He led his nearest teammates by three targets and five catches. That workload helped prop up an inefficient day on the ground, where McCaffrey managed a mere 3.1 yards per carry. His 73 receiving yards marked a solid 8.1-yard average. McCaffrey wound up with the third-best PPR score among RBs for the week (pending Monday night) even without scoring a TD.

49ers RB Christian McCaffrey (calf) is active for today’s game vs. the Seahawks. He popped up on Thursday’s injury report as limited and officially did not practice on Friday. McCaffrey went through an extensive warmup on Friday, though, and didn’t sound concerned about his status afterward. Fox Sports’ Jay Glazer reported this morning that scans on McCaffrey’s calf came back “completely clean.” There’s still some additional risk here, but CMC belongs in Week 1 fantasy lineups. RB Jordan James (finger) is inactive today, leaving RBs Brian Robinson and Isaac Guerendo behind McCaffrey.

ESPN's Adam Schefter reports that 49ers RB Christian McCaffrey (calf) will play vs. the Seahawks this afternoon. “He’s good to go,” a source said. Schefter reported earlier this morning that McCaffrey could be a game-time decision, but it sounds like the team has already determined that the calf is in good enough shape for him to suit up. There's still some elevated risk here, but McCaffrey would be impossible to leave out of Week 1 fantasy lineups.

NFL Network's Ian Rapoport confirms that 49ers RB Christian McCaffrey is still "trending" to play vs. the Seahawks this afternoon. McCaffrey was a "big part of walk-through on Saturday," Rapoport adds. While no one has flat-out guaranteed that McCaffrey will be active for the opener, it continues to sound likely that he plays. We'll get San Francisco's inactives a little after 2:30 pm ET.

49ers RB Christian McCaffrey (calf) is "likely" to play vs. the Seahawks on Sunday, according to NFL Network's Ian Rapoport.

49ers RB Christian McCaffrey (calf) told reporters after Friday's practice that he "feels great" and expects to play against the Seahawks on Sunday.

49ers RB Christian McCaffrey (calf) is listed as questionable for this weekend's game vs. the Seahawks. He was added to the injury report and limited in practice on Thursday and officially did not practice on Friday. McCaffrey was on the field going through warmups at the start of Friday's practice, though, and looked reasonably healthy. We'll surely get multiple updates on McCaffrey between now and kickoff on Sunday. Hopefully he's not a game-time decision, though, because 49ers-Seahawks doesn't kick off until 4:05 pm ET. McCaffrey's absence would leave Brian Robinson as San Francisco's lead back, although it's unclear exactly how big a role he'd be ready for after joining the team on August 22. RB Isaac Guerendo will also be available for the 'Niners, but RB Jordan James (finger) is doubtful.

"I do not get the sense based on the conversations I've had so far that there are alarm bells going off about Christian McCaffrey at this point," NFL Network's Tom Pelissero said Friday morning. It's just about the most positive update we could have hoped for after McCaffrey was added to Thursday's injury report with a calf. McCaffrey was not in the locker room after Thursday's workout and did not do his usual media session, according to ESPN's Nick Wagoner. We'll get another update on McCaffrey this afternoon when the 49ers release their final Week 1 injury report.

49ers RB Christian McCaffrey was added to the injury report and limited in practice on Thursday with a calf. Not what we wanted to see after last year's Achilles fiasco. We don't have any other details on McCaffrey's situation right now -- how serious the calf issue is or whether it's related to last year's Achilles trouble. We'll update his status as soon as we learn more. No. 2 RB Brian Robinson Jr. should be rostered in all fantasy leagues, and even No. 3 RB Isaac Guerendo is worth stashing for now in many spots.

The 49ers' trade for RB Brian Robinson appeared to cloud the depth chart behind RB Christian McCaffrey. HC Kyle Shanahan cleared that right up after Sunday's preseason finale, calling Robinson the "two back."

49ers’ second-string RB Isaac Guerendo returned to practice on Tuesday, according to Nick Wagoner of ESPN. Guerendo had been sidelined for multiple weeks with a shoulder injury.

Niners HC Kyle Shanahan told reporters Monday that all the team's "ACL guys" -- in the words of The Athletic's Matt Barrows -- are on track to return around Week 6. That includes WR Brandon Aiyuk, of course.