49ers WR Ricky Pearsall (knee, ankle) is inactive for tonight's game vs. the Seahawks. It's a surprise after he played last week and got in three limited practices this week. Pearsall's absence leaves Kendrick Bourne and Demarcus Robinson as San Francisco's No. 2 and 3 WRs -- and should mean more targets for RB Christian McCaffrey, TE George Kittle, and WR Jauan Jennings.

49ers QB Brock Purdy went 25/34 for 295 yards and 5 TDs with RB Christian McCaffrey going 21-117-0 on the ground and 6-29-2 on 8 targets through the air. The 49ers team put up 48 points on the Colts with Purdy tossing every TD except a late fourth-quarter pick-six from the defense. The 49ers' offense helped elevate playoff fantasy teams to make comebacks and could be league winners next week against the Bears.

49ers WR Ricky Pearsall (ankle, knee) is out for Monday night's game vs. the Colts. He didn't practice all week and could certainly miss multiple games after aggravating his PCL injury last week. Pearsall's absence boosts the target projections on WR Jauan Jennings and TE George Kittle.

The forecast for today's 49ers-Browns game calls for sustained winds of 25 mph with gusts around 35 mph. The total in this game has dropped from 42.5 to 35.5. Expect a run-heavy game plan from both sides. RBs Christian McCaffrey and Quinshon Judkins can stay in fantasy lineups. TE George Kittle is the only comfortable play from either passing game. Avoid the kickers.

The league has suspended Panthers S Tre'von Moehrig one game for punching 49ers WR Jauan Jennings ... in a sensitive area late in Monday night's contest. Jennings drew attention for an open-handed shot to Moehrig's head at the end of the game, but further review quickly revealed his motivation. Moehrig is appealing the ban.

Niners WR Ricky Pearsall managed just 1 catch for no yards among three targets in his return Sunday from a seven-week absence for a knee injury. But the outing was more encouraging than that would suggest.

49ers WR Ricky Pearsall (knee) is out for Sunday’s game vs. the Rams. He remained sidelined in practice all week. HC Kyle Shanahan said Friday that Pearsall still isn’t hitting his typical speeds on GPS and won’t be cleared to return until he does. Jauan Jennings and Kendrick Bourne will again operate as San Francisco’s top two WRs this weekend.

49ers WR Ricky Pearsall (knee) is out for Sunday’s game vs. the Giants. He remained sidelined in practice all week and still has no timetable for return. Jauan Jennings and Kendrick Bourne will continue to operate as San Francisco’s top two WRs in New York.

Niners WR Jauan Jennings won't win any Week 8 fantasy matchups with his 4 receptions for 45 yards in Sunday's loss to the Texans. But it marked a good outing for a receiver fighting through multiple injuries. Jennings led 49ers wideouts in total snaps and ran just one fewer route than WR Kendrick Bourne (30-31). Jennings' seven targets led the team by two, following another seven-target outing (last week) in which only Christian McCaffrey edged him. Jennings' consecutive 4-catch performances look good after his first four contests of the year produced reception totals of 2, 5, 2, and 1.

49ers WR Ricky Pearsall (knee) is out for Sunday’s game vs. the Texans. He remained sidelined in practice all week and has no timetable for return. Jauan Jennings and Kendrick Bourne will again operate as San Francisco’s lead WRs this week.

49ers WR Jauan Jennings (ankle, rib, shoulder) is not listed on the final injury report for Sunday night's game vs. the Falcons. He practiced all week, including a full workout on Friday. That's a big improvement over last week, when Jennings got in just limited practices on Thursday and Friday and was listed as questionable. Jennings said after that loss to the Buccaneers that he's playing through five broken ribs and high- and low-ankle sprains. He seems to be trending in the right direction now, although we'd still like to see him post a strong box score before trusting him in fantasy lineups.

49ers WR Jauan Jennings told reporters after Sunday's loss to the Buccaneers that he's playing through five broken ribs and high- and low-ankle sprains. That would explain his one-catch outing vs. Tampa Bay. We're still waiting for the official snap counts from this one, but Jennings was certainly not a full-time player. And he was clearly not anywhere close to 100%. We'll keep an eye on his practice participation going forward for signs of improving health. But Jennings will be very tough to trust in fantasy lineups until we see his snap rate and production rebound to normal levels. His injuries also make WR Kendrick Bourne a more intriguing fantasy play, even if WR Ricky Pearsall and TE George Kittle return for Week 7.

49ers WR Jauan Jennings (ankle, rib) is active for today’s game vs. the Buccaneers. He got in just limited practices on Thursday and Friday, so it’s safe to assume he won’t be at 100% for this one. But Jennings boasts exciting target upside with WRs Ricky Pearsall and Brandon Aiyuk and TE George Kittle out.

49ers WR Jauan Jennings (ankle, rib) is expected to play vs. the Buccaneers today, according to ESPN's Adam Schefter. Jennings is listed as questionable after getting in just limited practices on Thursday and Friday, so it's fair to assume he won't be at 100% for this one. But there's plenty of target upside with WRs Ricky Pearsall and Brandon Aiyuk and TE George Kittle out. Consider Jennings a risk/reward play in Week 6 fantasy lineups -- and check your Team Intel page to see if he belongs in your starting lineup.

49ers WR Jauan Jennings (ankle, rib) is listed as questionable for this weekend's game vs. the Buccaneers. He got in limited practices on Thursday and Friday. The Niners could certainly use Jennings in this one, with WR Ricky Pearsall, WR Brandon Aiyuk, and TE George Kittle all still out. Jennings will boast plenty of target upside if he's able to go. We'll look for further updates on his status but won't get San Francisco's inactives until a little before 3 pm ET on Sunday.

WR Ricky Pearsall has officially been ruled out for San Francisco's Week 6 trip to Tampa Bay to take on the Buccaneers. Pearsall will miss his second consecutive game with a PCL injury. The 49ers will also be without QB Brock Purdy (toe) and TE George Kittle (hamstring).

49ers WR Ricky Pearsall (knee) remained sidelined for Thursday's practice. He's looking like a long shot to play vs. the Buccaneers this weekend. WR Jauan Jennings (ankle, rib) returned to a limited practice on Thursday, giving him a shot to suit up on Sunday. We'll get another update on both of these guys on Friday afternoon.

49ers WRs Ricky Pearsall (knee) and Jauan Jennings (ankle, rib) did not practice on Wednesday. HC Kyle Shanahan admitted afterward that the team “is not counting” on having Pearsall back this week. It sounds like Jennings has a better chance of playing against the Buccaneers on Sunday, although he's still very uncertain. We'll keep you updated on the situation over the next few days. WR Kendrick Bourne will be a low-end fantasy starter if just one of Pearsall and Jennings play; an upside WR3 if both guys miss.

49ers WR Kendrick Bourne exploded for 10 catches and 142 yards in Thursday night's overtime win vs. the Rams. His 11 targets tied for the team lead and were a 22.4% share. Bourne consistently created separation on short and intermediate routes and was clearly QB Mac Jones' most trusted WR on a night when Ricky Pearsall, Jauan Jennings, and Brandon Aiyuk were all out. Jones and Bourne played together in New England from 2021 to 2023, and they clearly still have chemistry.