The Bengals have placed RB Samaje Perine on the COVID list. His specific status isn't yet clear, but he at least looks very iffy for Week 6. Perine isn't much of a standalone fantasy option when Joe Mixon is healthy, but he did eat up 11 carries (for 59 yards) and catch 4 balls for 24 yards and a TD in Sunday's loss to the Packers. Perine played more than 3 times as many snaps as Mixon in that game and beat him in rushing attempts and targets. As long as Mixon avoids any setback with his sprained ankle, we'd assume more work for the starter in this Sunday's visit to Detroit. If Perine is out, then Chris Evans should see some involvment. We wouldn't expect him to be an option for fantasy football lineups, though.