Chiefs RB Isiah Pacheco (knee) is trending toward a return for Thursday's game vs. the Cowboys, according to ESPN's Jeremy Fowler. Pacheco practiced all last week but was held out of the Colts game. "I think he's coming out pretty good," HC Andy Reid said of Pacheco on Friday. "I think that's a plus." Pacheco had emerged as Kansas City's lead back ahead of Kareem Hunt prior to going down in Week 8, but it's unclear exactly what the backfield will look like in Dallas on Thanksgiving. Consider both Pacheco and Hunt risk/reward RB3s in Week 13 fantasy lineups.

Buccaneers QB Baker Mayfield (shoulder) "has a real chance" to play vs. the Cardinals this weekend, according to NFL Network's Ian Rapoport. Monday's MRI revealed a "low-grade" AC joint sprain in his left shoulder, per Rapoport. We'll track Mayfield's progress throughout the week. QB Teddy Bridgewater would be a big downgrade for the offense if Mayfield is unable to play.

Raiders HC Pete Carroll called RB Ashton Jeanty's ankle injury a "tweak" and "not severe" on Monday. "It sounds like there’s a chance that he would be okay," Carroll added. We'll start the week projecting Jeanty to play vs. the Chargers but keep a close eye on his practice participation.

Commanders WR Terry McLaurin (quad) was on the field for Monday's post-bye-week practice and seemingly has a shot to return for Sunday night's game vs. the Broncos. "I’ll have a better answer later," HC Dan Quinn said when asked about McLaurin's Week 13 status. "I will say that I’m excited about the possibilities, because of his speed and how he’s moving. Those are big steps." We'll keep you updated on McLaurin's status throughout the week. If he does play on Sunday, he'd be no better than a WR3 against Denver's second-ranked WR defense.

The Bears quietly placed LB Tremaine Edmunds on IR over the weekend, ahead of Sunday's win over the Steelers. That means Edmunds' groin injury will cost him at least three more games.

Bengals HC Zac Taylor said Monday that Edge Trey Hendrickson will miss Thursday's game against the Ravens. It'll be his fourth straight game lost to a hip injury. Even the game before that found Hendrickson trying to play through the issue but leaving early. Cincinnati has managed just four total sacks without Hendrickson over the past three contests and finished five of the past six games with one sack or fewer.

Dallas' offense started sluggishly in Sunday's win over the Eagles, failing to cross the 50-yard line until its third possession and fumbling that one away. Philadelphia jumped to a 21-0 lead before the middle of the second quarter, and QB Dak Prescott followed that third enemy score by throwing an INT into the end zone. But he rebounded big time from there to rack up 354 yards, 2 TDs and a rushing score. The game finished with his second-best fantasy score of the season and the third-best among QBs for the week (with Monday night's game left to go). Prescott now ranks among the top 5 per-game scorers at the position for the season (depending on your format).

Rams RB Kyren Williams watched his offense gain 333 net yards and tally 34 points in a home win over Tampa Bay. The 25-year-old wasn’t a main contributor, though, mustering only 46 yards on 12 attempts. He caught one pass for 2 yards.

Commanders QB Jayden Daniels (elbow) will return to practice this week but is considered a "long shot" to play vs. the Broncos on Sunday night, according to NFL Network's Ian Rapoport. It looks like Daniels will get medical clearance to play before the end of the season, but it's still uncertain whether the 3-8 Commanders will throw him back out there. We'll keep you updated on Daniels' status. QB Marcus Mariota is in line to start against Denver this weekend but will only be in play in 2-QB and Superflex leagues.

Jaguars RB Travis Etienne led the backfield with 86 yards on 15 attempts in Sunday’s win over Arizona. He added 3 catches for 30 yards and his first receiving score since Week 2.

Bengals HC Zac Taylor stopped short of guaranteeing that QB Joe Burrow (toe) will play vs. the Ravens on Thursday night, but he said he "anticipates" him getting the start. Burrow, meanwhile, posted "He's back" on his social media on Monday. All signs point to him making his return for this game against a division rival that he smoked for 392-5-1 and 428-4-0 passing lines last year. Burrow will be a risk/reward Week 13 fantasy start in his first action in more than two months -- and without WR Tee Higgins.

Bengals WR Tee Higgins (concussion) won't play against the Ravens on Thursday night, HC Zac Taylor said Monday. Higgins suffered a scary looking concussion in the Week 12 loss to the Patriots and was never going to clear protocol on the short week. Cincinnati gets WR Ja'Marr Chase back this week, and he should dominate targets against Baltimore. But Higgins' absence puts WR Andrei Iosivas and TE Mike Gesicki in play as low-end fantasy options.

Patriots RB TreVeyon Henderson remained the clear lead back in Week 12, despite the return of Rhamondre Stevenson. The rookie out-carried Stevenson 18-6 and topped him in targets, 4-2.

Cowboys WR CeeDee Lamb should have posted a much better fantasy line than he did in Sunday's win over the Eagles. He did manage 75 yards on 4 catches, but Lamb drew a team-high 11 targets in the contest. Pro Football Focus charged him with two drops, including one in the end zone. (Others had him for three in the game.) That's a particularly interesting point, because Lamb had a similar issue at Philadelphia in the opener. For the season, PFF has charged Lamb with eight drops in eight games. Six of those have come against the Eagles.

When the Cowboys visited Philadelphia to open the season, WR George Pickens tallied just 3 receptions in his first game with the team. Dallas channeled bigger target loads to CeeDee Lamb and Jake Ferguson in that game. But Pickens made a much larger impact on Sunday's rematch victory. He snagged all nine of his targets for a game-high 146 yards and a TD. It was Pickens' second straight game with 9 receptions and at least 144 yards. It was his fourth consecutive week with at least nine targets.

The Eagles jumped out to a 21-0 lead before the middle of the second quarter in Sunday's visit to Dallas, with two of their TDs coming on the ground. Sounds like the ideal environment for RB Saquon Barkley, right? Nope. Barkley got just six first-half carries (for 13 yards) vs. the team's 19 pass attempts. He finished with just 10 rushes for 22 yards against a Cowboys defense that still ranks a lowly 29th in rush DVOA. Barkley did, at least, save his fantasy day with 7 receptions for 52 yards. He ranked second on the team in catches; third in targets and receiving yards.

The Vikings have placed QB J.J. McCarthy in the concussion protocol, per HC Kevin O’Connell. As of now, O'Connell says “it’s too early to tell” who’ll be under center for the Vikings in Week 13.

Browns HC Kevin Stefanski said Monday that QB Dillon Gabriel has cleared the concussion protocol but that Shedeur Sanders will maintain the No. 1 QB role for next Sunday's home date with the 49ers. Sanders threw for 209 yards and a TD in Sunday's win over the Raiders, becoming the first Cleveland QB to win his starting debut since Eric Zeier in 1995.

Eagles WR DeVonta Smith posted a solid receiving line in Sunday's come-from-ahead loss to the Cowboys: 6 receptions for 89 yards. He even drew a team-high 11 targets, edging A.J. Brown by one. That followed games of seven and five targets for Smith and marked just the third time this season he reached double digits. Part of that is Philly's low-volume passing offense, but Smith also might have an emerging issue in the team's shift toward Brown.

Eagles WR A.J. Brown racked up 8 receptions for 110 yards and a TD in Sunday's loss to the Cowboys. His 10 targets trailed WR DeVonta Smith's team lead by one but marked his second straight game of 10+ after five consecutive outings of single-digit targets.