Cardinals WR Rondale Moore (hamstring) remained sidelined on Wednesday. Fantasy owners can't count on him playing vs. the Raiders this weekend. With Moore out last week, WR Greg Dortch stepped in for a 96% route rate and 7-63 line on 9 targets. He's a spot-start option in deeper PPR leagues if Moore is out.
Seahawks RB Kenneth Walker (hernia) was a full participant in Wednesday's practice. That puts him on track to play vs. the 49ers this weekend. Walker figures to play well behind RB Rashaad Penny in his NFL debut, so he's not a recommended Week 2 fantasy play. But the talented rookie could quickly earn a significant role and should be rostered in leagues of 10+ teams.
Lions RB D'Andre Swift missed Wednesday's practice with an ankle injury. He didn't appear limited at all during Sunday's loss to the Eagles. We'll see about the severity of the ailment. Jamaal Williams would be in for a big workload boost if Swift misses time.
Broncos HC Nathaniel Hackett told reporters Wednesday that S Justin Simmons will miss "some time" with a thigh injury he suffered in Monday night's opener. NFL Network's James Palmer reports that he's "hearing" Simmons will land on short-term IR. That would mean at least 4 missed games. Caden Sterns and P.J. Locke look like the fill-in candidates. Denver also added S Anthony Harris to the practice squad Wednesday.
Chargers WR Keenan Allen (hamstring) is out for Thursday night's game vs. the Chiefs. His injury isn't believed to be serious, but he was always unlikely to play on the short week. We'll see if he can make it back for Week 3. Allen's absence will push Josh Palmer onto the field in 2-WR sets and puts him on the WR3/Flex radar.
Packers LB Quay Walker took the field for Wednesday's practice after leaving the opener with a shoulder injury, according to ESPN's Rob Demovsky. It looks like we should expect the rookie to be in the lineup for Sunday night's game against the Bears. We'll watch his practice participation to confirm.
The Chiefs have ruled K Harrison Butker (left ankle) out for Thursday night's game against the Chargers. Matt Amendola is expected to kick in his absence, according to NFL Network's Ian Rapoport.
ESPN's Jeremy Fowler reports that Raiders LB Denzel Perryman is considered day-to-day with the ankle injury that knocked him out of Sunday's loss to the Chargers. That puts Perryman in play for Week 2. We'll watch his status through the practice week. Divine Deablo led Vegas LBs in playing time in Perryman's absence, with Jayon Brown trailing.
Giants WR Wan'Dale Robinson (knee) did not practice on Wednesday. We still don't have any details on his injury, but ESPN's Jordan Raanan reports that Robinson had a brace on his right knee and said, "it certainly looks like he'll miss some time." The rookie is not a must-hold on redraft rosters.
Bengals WR Tee Higgins (concussion) was able to put in a limited practice on Wednesday. That means he's made some progress through the protocol and has a shot to be cleared for Sunday's game vs. the Cowboys. We'll continue to monitor his progress.
Colts WR Alec Pierce developed concussion symptoms in the wake of Sunday's game against the Texans and has entered the league protocol, HC Frank Reich told reporters Wednesday. We'll see whether Pierce can get through ahead of Sunday's game. Pierce ranked 3rd on the team in route rate and drew only 2 targets in the opener, so he shouldn't be near fantasy lineups even if he's back.
Cowboys HC Mike McCarthy said WR Michael Gallup (knee) will take team reps in Wednesday's practice for the 1st time since last January's ACL tear. It's unclear if Gallup will play against the Bengals this weekend, but he looks close to a return. Of course, Gallup will be tough to get excited about in fantasy lineups until Dallas gets QB Dak Prescott back.
Seahawks HC Pete Carroll said Tuesday that RB Kenneth Walker (hernia) will play in this weekend's game vs. the 49ers. We'll wait to see if Walker gets on the practice field this week before adding him to the Week 2 Rankings. If Walker plays, he figures to debut as the clear #2 RB behind Rashaad Penny.
The Colts released K Rodrigo Blankenship. He missed a 42-yard FG to win the game in overtime last week. The Colts haven't signed a replacement yet.
The 49ers signed RB Marlon Mack to their practice squad. San Francisco, of course, will be without RB Elijah Mitchell (knee) for the next couple of months. Mack couldn't make the Texans' roster, though, and is unlikely to be a factor with the 'Niners.
Chiefs K Harrison Butker (ankle) missed his 2nd straight practice on Tuesday. He was able to battle through this injury in the opener, but Butker shouldn't be considered a lock to play vs. the Chargers on Thursday night. We'll update his status again tomorrow.
The Patriots placed RB Ty Montgomery on IR. No word yet on the specific injury, but he's out for at least the next 4 games. Montgomery finished 2nd among Patriots RBs in snaps (36%) and tied Damien Harris for the RB lead in routes (31%) in Sunday's loss to the Dolphins, finishing with 2 carries and 4 targets. His absence opens up considerable opportunity in the passing game. It's uncertain whether Harris, RB Rhamondre Stevenson or possibly even RB Pierre Strong will capture it.
Seahawks WR Tyler Lockett mustered only 3 catches for 28 yards in Week 1. He saw 4 targets — tied with TE Noah Fant for 2nd most on the team — but didn’t see any downfield opportunities. In fact, while QB Geno Smith played efficient ball, his average depth of target (aDOT) was a week-low 5.0 yards. At least in the short term, Lockett’s best treated as a WR4.
Steelers RB Najee Harris (foot) said in a Tuesday radio appearance that he'll play vs. the Patriots this weekend. Players, of course, are always optimistic about their status. But we've heard independent reports that Harris' injury isn't serious and that he's likely to play Week 2. He can stay penciled into fantasy lineups for now.
NFL Network's Tom Pelissero reports that Chargers WR Keenan Allen's hamstring injury is not expected to be a "long-term" deal. But Pelissero confirms that Allen is "unlikely" to be ready for Thursday night's showdown with the Chiefs. That's obviously a big loss for the Chargers but frees up targets for Austin Ekeler, Mike Williams, Josh Palmer and Gerald Everett. See where all those guys sit in the Week 2 Rankings.
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