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        Week 6 Matchups That Matter: Breakout Spot For Tetairoa McMillan?

        A quick look at the most important matchup data to consider when making Week 6 start/sit decisions. Projected points, WR-CB matchup upgrades and downgrades, and more!
        By Jared Smola | Updated on Sun, Oct 12 2025 3:01 PM UTC
        Week 6 Matchups That Matter: Breakout Spot For Tetairoa McMillan?

               

        Welcome to Week 6’s Matchups That Matter.

        Want a peek behind the curtain?

        This article walks you through the process that powers our weekly projections and rankings. Below, you’ll find the key metrics and data we lean on to set those numbers, so you can make sharper start/sit calls every week.

        When you’re ready to set your lineup, hit the Week 6 Rankings and your Team Intel page for personalized advice.

        Good luck in Week 6!

           

        Jump to:

           

        Highest Game Totals

        1. Lions at Chiefs (52.5)
        2. Bills at Falcons (50.0)
        3. Bears at Commanders (49.5)
        t-4. Seahawks at Jaguars (47.5)
        t-4. Cowboys at Panthers (47.5)
        t-6. 49ers at Buccaneers (46.5)
        t-6. Cardinals at Colts (46.5)

            

        Lowest Game Totals

        12. Broncos vs. Jets (43.5)
        13. Titans at Raiders (41.5)
        14. Eagles at Giants (40.5)
        15. Browns at Steelers (38.5)

               

        Projected Points

        We can use Vegas lines to calculate how many points each team is projected to score this week.

        Here's how each team stacks up:

        Week 6 projected points

        TIP

        Projected points are built into our award-winning fantasy rankings.

         

        Most Projected Points

        1. Packers (29.5)
        2. Colts (28.0)
        3. Chiefs (27.5)
        4. Bills (27.25)
        5. Commanders (27.0)

          

        Fewest Projected Points

        t-25. Cardinals (18.5)
        t-25. Titans (18.5)
        27. Jets (18.25)
        28. Giants (16.5)
        29. Browns (16.0)
        30. Bengals (15.0)

            

        Projected Plays

        The chart below shows how many plays we're projecting each team to run vs. the league average for the week. More plays = more chances for fantasy points.

        Week 6 projected plays

         

        Most Projected Plays

        1. Packers (63.8)
        2. Saints (63.5)
        3. Cowboys (63.4)
        4. Broncos (63.3)
        5. Rams (63.1)

         

        Fewest Projected Plays

        26. Jets (60.8)
        27. Titans (60.6)
        28. Dolphins (60.3)
        29. Ravens (59.8)
        30. Bengals (59.7)

          

        Pace Matchups

        The chart below displays how each game stacks up in terms of pace vs. the league average for the week. Pace is calculated by averaging the situation-neutral seconds per snap from both teams in each game. Faster-paced games often produce more plays, which means more fantasy points.

        Week 6 pace matchups

         

        Fastest-Paced Games (Average of neutral seconds/snap)

        1. Patriots at Saints (25.5 seconds)
        2. Bears at Commanders (26.9 seconds)
        3. Bengals at Packers (27.0 seconds)
        4. 49ers at Buccaneers (27.2 seconds)
        5. Seahawks at Jaguars (27.2 seconds)

         

        Slowest-Paced Games (Average of neutral seconds/snap)

        11. Lions at Chiefs (28.4 seconds)
        12. Broncos vs. Jets (28.6 seconds)
        t-13. Eagles at Giants (28.7 seconds)
        t-13. Cardinals at Colts (28.7 seconds)
        15. Bills at Falcons (29.7 seconds)

                

        Weather Concerns

        Cowboys at Panthers

        Winds are forecasted at 15-16 mph, with gusts up to 30 mph. That could impact some deep throws and kicks, but we're not adjusting projections here. The over/under on this game has dropped two points but is still sitting at a healthy 47.5.

        Rams at Ravens

        Similar forecast as Charlotte. Winds of 16-17 mph with gusts up to 30 mph. We could see that impact some deep throws and kicks, but it's not enough to adjust projections.

          

        Quarterback

        Passing Matchups 

        The chart below plots each team's pass offense DVOA vs. their opponent's pass defense DVOA.

        Week 6 passing matchups

         

        5 Best Passing Matchups (sum of pass offense DVOA and opponent pass defense DVOA)

        1. Packers vs. Bengals (+75.3%)
        2. Patriots at Saints (+72.4%)
        3. Rams at Ravens (+71.3%)
        4. Broncos vs. Jets (+66.0%)
        t-5. Seahawks at Jaguars (+57.2%)
        t-5. Chargers at Dolphins (+57.2%)

         

        5 Worst Passing Matchups (sum of pass offense DVOA and opponent pass defense DVOA)

        26. Cardinals at Colts (-8.9%)
        27. Giants vs. Eagles (-12.9%)
        28. Titans at Raiders (-18.6%)
        29. Browns at Steelers (-20.0%)
        30. Bengals at Packers (-36.8%)

         

        5 Best QB Matchups (based on 2025 adjusted fantasy points allowed)

        1. Jordan Love vs. Bengals (+66.8%)
        2. Bryce Young vs. Cowboys (+63.3%)
        3. Matt Stafford at Ravens (+49.0%)
        4. Caleb Williams at Commanders (+30.4%)
        5. Dillon Gabriel at Steelers (+27.5%)

        Headshot of Jordan Love

                

        5 Worst QB Matchups (based on adjusted 2025 fantasy points allowed)

        26. Cam Ward at Raiders (-18.4%)
        27. Aaron Rodgers vs. Browns (-22.4%)
        28. Jaxson Dart vs. Eagles (-22.6%)
        29. Josh Allen at Falcons (-28.3%)
        30. Jared Goff at Chiefs (-34.1%)

        Week 6 QB Rankings

           

        Running Back

        Rushing Matchups 

        The chart below plots each team's run offense DVOA vs. their opponent's run defense DVOA.

        Week 6 rushing matchups

         

        5 Best Rushing Matchups (sum of rush offense DVOA and opponent rush defense DVOA)

        1. Eagles at Giants (+18.8%)
        2. Rams at Ravens (+6.9%)
        3. Commanders vs. Bears (+3.6%)
        4. Chargers at Dolphins (-1.3%)
        5. Falcons vs. Bills (-3.0%)

         

        5 Worst Rushing Matchups (sum of rush offense DVOA and opponent rush defense DVOA)

        26. Buccaneers vs. 49ers (-38.9%)
        27. Steelers vs. Browns (-41.9%)
        28 Bengals at Packers (-47.7%)
        29. 49ers at Buccaneers (-51.0%)
        30. Bears at Commanders (-52.2%)

               

        5 Best RB Matchups (based on adjusted 2025 fantasy points allowed)

        1. Panthers vs. Cowboys (+59.6%)
        2. Raiders vs. Titans (+54.2%)
        3. Rams at Ravens (+44.6%)
        4. Eagles at Giants (+39.8%)
        5. Packers vs. Bengals (+39.0%)

        Headshot of Rico Dowdle

                  

        5 Worst RB Matchups (based on adjusted 2025 fantasy points allowed

        26. Bears at Commanders (-21.5%)
        27. Ravens vs. Rams (-23.7%)
        28. Bengals at Packers (-32.9%)
        29. Bills at Falcons (-38.5%)
        30. Steelers vs. Browns (-39.8%)

        Week 6 RB Rankings

          

        Wide Receiver

        5 Best WR Matchups (based on adjusted 2025 fantasy points allowed)

        1. Panthers vs. Cowboys (+67.5%)
        2. Seahawks at Jaguars (+41.8%)
        3. Browns at Steelers (+38.7%)
        4. Ravens vs. Rams (+38.6%)
        5. Rams at Ravens (+33.5%)

        Headshot of Tetairoa McMillan

              

        5 Worst WR Matchups (based on adjusted 2025 fantasy points allowed)

        26. Bills at Falcons (-16.6%)
        27. Jets vs. Broncos (-18.3%)
        28. Lions at Chiefs (-22.1%)
        29. Dolphins vs. Chargers (-28.9%)
        30. Giants vs. Eagles (-30.5%)

        Week 6 WR Rankings

            

        WR/CB Matchup Upgrades

        Lions WR Amon-Ra St. Brown vs. Chiefs CB Chamarri Conner

        Chiefs WRs Xavier Worthy and Marquise Brown vs. Lions CBs Amik Robertson, Rock Ya-Sin, and Avonte Maddox

        Chargers WRs Ladd McConkey and Keenan Allen vs. Dolphins CBs Jack Jones, Rasul Douglas, and Cornell Armstrong

        Panthers WR Tetairoa McMillan vs. Cowboys CBs Trevon Diggs and Kaiir Elam

        Cardinals WR Marvin Harrison Jr. vs. Colts CBs Charvarius Ward and Mekhi Blackmon

        Patriots WR Stefon Diggs vs. Saints CBs Kool-Aid McKinstry and Quincy Riley

        Broncos WR Troy Franklin vs. Jets CBs Brandon Stephens and Malachi Moore

         

        WR/CB Matchup Downgrades

        Jets WR Garrett Wilson vs. Broncos CB Pat Surtain

        Bears WRs Rome Odunze and D.J. Moore vs. Commanders Marshon Lattimore and Trey Amos

        Lions WR Jameson Williams vs. Chiefs CBs Trent McDuffie and Jaylen Watson

        Bills WR Keon Coleman vs. Falcons CBs A.J. Terrell and Mike Hughes

        Giants WR Wan'Dale Robinson vs. Eagles CB Cooper DeJean

        Seahawks WR Cooper Kupp vs. Jaguars CB Jourdan Lewis

               

        Tight End

        5 Best TE Matchups (based on adjusted 2025 fantasy points allowed)

        1. Broncos vs. Jets (+68.0%)
        2. Packers vs. Bengals (+65.5%)
        3. Broncos at Steelers (+53.5%)
        4. Cardinals at Colts (+47.3%)
        5. 49ers at Buccaneers (+47.3%)

        Headshot of Evan Engram

                  

        5 Worst TE Matchups (based on adjusted 2025 fantasy points allowed)

        26. Titans at Raiders (-28.4%)
        27. Lions at Chiefs (-28.9%)
        28. Giants vs. Eagles (-30.3%)
        29. Falcons vs. Bills (-54.5%)
        30. Bills at Falcons (-64.1%)

        Week 6 TE Rankings

                

        Defense/Special Teams

        5 Best DST Matchups (based on adjusted 2025 fantasy points allowed)

        1. Steelers vs. Browns (+421.7%)
        2. Eagles at Giants (+120.0%)
        3. Titans at Raiders (+90.6%)
        4. Packers vs. Bengals (+77.1%)
        5. Broncos vs. Jets (+72.6%)

               

        5 Worst DST Matchups (based on adjusted 2025 fantasy points allowed)

        26. Seahawks at Jaguars (-50.7%)
        27. Lions at Chiefs (-71.4%)
        28. Panthers vs. Cowboys (-71.6%)
        29. Chiefs vs. Lions (-80.3%)
        30. Cardinals at Colts (-97.3%)

        TIP

        Check out the top Week 6 DST Streamers.

           

        Kicker

        5 Best K Matchups (based on 2025 fantasy points allowed)

        1. Wil Lutz vs. Jets (+102.6%)
        2. Joey Slye at Raiders (+39.3%)
        3. Michael Badgley vs. Cardinals (+28.0%)
        4. Matt Prater at Falcons (27.3%)
        5. Joshua Karty at Ravens (+26.9%)

               

        5 Worst K Matchups (based on 2025 fantasy points allowed)

        26. Jason Myers at Jaguars (-23.3%)
        27. Andre Szmyt at Steelers (-27.0%)
        28. Chad Ryland at Colts (-29.7%)
        29. Harrison Butker vs. Lions (-32.1%)
        30. Chase McLaughlin vs. 49ers (-39.0%)

        Week 6 K Rankings

                 

        Jared Smola Author Image
        Jared Smola, Lead Analyst
        Jared has been with Draft Sharks since 2007. He’s now Lead Analyst, heading up the preseason and weekly projections that fuel your Draft War Room and in-season tools. He currently ranks ninth among 173 analysts in draft rankings accuracy.
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